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MB67 (T102) Peptide

Cat no: BS2311P

MB67 (T102) Peptide

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

BS2311P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide MB67 (T102). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q14994

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2311 MB67 (T102) pAb.

Alternative Names

Constitutive androstane receptor; CAR; Orphan nuclear receptor MB67; NR1I3; AA209988. AI551208. CAR. CAR1. CAR2. Care2. ESTM32. MB67. MGC107281. Mcar

SUPPLIER INFO

Bioworld Technology, Inc.

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