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Mcl-1 (S155) pAb

Mcl-1 (S155) pAb

Cat no: BS2642

Supplier: Bioworld Technology, Inc.
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Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.
Catalogue number: BS2642
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q07820
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 130-180 of Human Mcl-1.
Species: Mcl-1 (S155) pAb detects endogenous levels of Mcl-1 protein.
Molecular weight: ~ 37 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Induced myeloid leukemia cell differentiation protein Mcl 1; Myeloid Cell Leukemia 1; BCL2 related; EAT; MCL1L; MCL1S; MGC1839; myeloid cell leukemia sequence 1; TM; MGC104264; MCL 1; Bcl 2 related protein EAT/mcl1; Mcl1/EAT; Myeloid cell leukemia se
Additional info: For research use only, not for use in diagnostic procedure.

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