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MCM2 / BM28 (A11) Peptide

MCM2 / BM28 (A11) Peptide

Cat no: BS1221P

Supplier: Bioworld Technology, Inc.
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The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATPbinding motif, which is predicted to mediate ATP-dependent opening of doublestranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the ostreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro.
Catalogue number: BS1221P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49736
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MCM2 / BM28 (A11). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog Nuclear protein BM28; MCM2; BM28; CCNL1; CDCL1; KIAA0030
Additional info: This peptide can be used with studies using BS1221 MCM2 / BM28 (A11) pAb.

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