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MED18 (V102) Peptide

MED18 (V102) Peptide

Cat no: BS3141P

Supplier: Bioworld Technology, Inc.
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In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med18 (mediator complex subunit 18), also known asp28b, is a 208 amino acid protein that localizes to nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med18 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes.
Catalogue number: BS3141P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9BUE0
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MED18 (V102). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Mediator of RNA polymerase II transcription subunit 18; Mediator complex subunit 18; p28b; MED18
Additional info: This peptide can be used with studies using BS3141 MED18 (V102) pAb.

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