MEK-4/ MAP2K4 (E74) pAb

Cat no: BS1320

Supplier: Bioworld Technology, Inc.

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The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38(beta). MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Catalogue number:	BS1320
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	P45985
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 50-100 of Human MEK-4.
Species:	SEK1/MKK4 (E74) pAb detects endogenous levels of SEK1/MKK4 protein.
Molecular weight:	~ 44 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	MAP2K4; EC 2.7.12.2; JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SERK1
Additional info:	For research use only, not for use in diagnostic procedure.

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MEK-4/ MAP2K4 (E74) pAb

Cat no: BS1320

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