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MEK Kinase-3 (N96) Peptide

MEK Kinase-3 (N96) Peptide

Cat no: BS2129P

Supplier: Bioworld Technology, Inc.
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Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also called MAP kinase kinase kinases) phosphorylate and activate the MAP kinases, including ERK, JNK and p38. The MEK kinases characterized to date include Raf-1, Raf-B, MOS, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (also designated MEK kinase-5). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.
Catalogue number: BS2129P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q99759
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MEK Kinase-3 (N96). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3
Additional info: This peptide can be used with studies using BS2129 MEK Kinase-3 (N96) pAb.

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