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Melanopsin (L470) pAb

Cat no: BS2859

Melanopsin (L470) pAb

Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.

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SPECIFICATIONS

Catalog Number

BS2859

Size

100ug/100ul

Applications

IF, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 440-486 of Human Melanopsin.

Species

Melanopsin (L470) pAb detects endogenous levels of Melanopsin protein.

Dilutions

WB: 1:500~1:1000\nIF: 1:50~1:200

Swiss Prot

Q9UHM6

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 55 kDa

Alternative Names

Melanopsin; Intrinsically photosensitive retinal ganglion cells; ipRGC; ipRGCs

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