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mGluR-6 (A865) pAb

mGluR-6 (A865) pAb

Cat no: BS1146

Supplier: Bioworld Technology, Inc.
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The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.
Catalogue number: BS1146
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: O15303
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 841-890 of Human mGluR-6.
Species: mGluR6 (A865) pAb detects endogenous levels of mGluR6 protein.
Molecular weight: ~ 100 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6
Additional info: For research use only, not for use in diagnostic procedure.

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