Mlx (Q136) Peptide

Cat no: BS2160P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad 1, Mad 3, Mad 4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad 1, Mad 4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.

Catalogue number:	BS2160P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9UH92
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Mlx (Q136). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	MLXIPL; CHREBP. MIO. MONDOB. WBSCR14. WS-bHLH
Additional info:	This peptide can be used with studies using BS2160 Mlx (Q136) pAb.

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Mlx (Q136) Peptide

Cat no: BS2160P

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