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MMP-10 (I387) Peptide

Cat no: BS1551P

MMP-10 (I387) Peptide

Proteins of the matrix metalloproteinase (MMP) family are zinc containing proteolytic enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They also play an important role in apoptosis, tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Most of the MMP's contain a common domain structure, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 degrades proteoglycans, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. and fibronectin. It activates procollagenase. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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SPECIFICATIONS

Catalog Number

BS1551P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide MMP-10 (I387). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P09238

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1551 MMP-10 (I387) pAb.

Alternative Names

Stromelysin-2; Stromelysin2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2; MMP10; STMY2

SUPPLIER INFO

Bioworld Technology, Inc.

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