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MMP-8 (F445) pAb

MMP-8 (F445) pAb

Cat no: BS1240

Supplier: Bioworld Technology, Inc.
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The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-8 (also designated neutrophil collagenase, PMNL collagenase or collagenase-2) degrades fibrillar collagen types I, II and III. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is highly expressed in the postpartum uterus, and it is thought to be involved in the postpartum involution of the uterus. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.
Catalogue number: BS1240
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P22894
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 415-460 of Human MMP-8.
Species: MMP-8 (F445) pAb detects endogenous levels of MMP-8 protein.
Molecular weight: ~ 55 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: MMP8; CLG1; EC 3.4.24.34; HNC; MMP-8; PMNL-CL
Additional info: For research use only, not for use in diagnostic procedure.

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