MOX-2 (N184) Peptide

Cat no: BS2006P

Supplier: Bioworld Technology, Inc.

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Closely related homeobox proteins, MOX-1 and MOX-2, belong to a family of nonclustered, diverged homeobox genes that are expressed in overlapping patterns in the paraxial mesoderm and its derivatives. MOX-1 and MOX-2 function transiently in the formation of mesodermal and mesenchymal derivatives. MOX-1 and MOX-2 are implicated in the early steps of mesoderm formation during gastrulation. In addition, the MOX proteins are also involved in somatic differentiation. Significantly, MOX-1 associates more strongly with Pax1, whereas MOX-2 preferentially associates with Pax3. Specifically, expression of MOX-2, also known as Mesenchyme homeobox 2 and GAX, has been shown to be critical in axial skeleton development. MOX-2 is not needed for the migration of myogenic precursors into the limb bud, but it is essential for normal appendicular muscle formation and for the normal regulation of myogenic genes. MOX-2 is expressed in placental tissue. The human MEOX2 gene maps to chromosome 7p22.1-p21.3 and encodes the MOX-2 protein. Mutations in the gene may be involved in craniofacial and/or skeletal abnormalities.

Catalogue number:	BS2006P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P50222
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide MOX-2 (N184). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	MEOX2; GAX; MOX2
Additional info:	This peptide can be used with studies using BS2006 MOX-2 (N184) pAb.

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MOX-2 (N184) Peptide

Cat no: BS2006P

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