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MRP-L12 pAb

MRP-L12 pAb

Cat no: BS5802

Supplier: Bioworld Technology, Inc.
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MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion. MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs. Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation. MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit. MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.
Catalogue number: BS5802
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P52815
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 75-120 of Human MRP-L12.
Species: MRP-L12 pAb detects endogenous levels of MRP-L12 protein.
Molecular weight: ~ 21 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 39S ribosomal protein L12, mitochondrial; L12mt; MRP-L12; 5c5-2; MRPL12; RPML12
Additional info: For research use only, not for use in diagnostic procedure.

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