MRP3 (Multidrug Resistance-associated Protein 3, ABC31, ATP Binding Cassette Sub-family C Member 3, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 3, ABCC3, Canalicular Multispecific Organic Anion Transporter 2, CMOAT2, DKFZp686E22157, EST90757, MLP2

Applications:\nSuitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and Flow Cytomtry. Other applications not tested.\n\nRecommended Dilution:\nImmunocytochemistry (acetone or formaldehyde-fixed): 1:20-1:50 \nImmunohistochemistry (acetone fixed frozen): 1:20 \nWestern Blot: 1:20-1:50 \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

M4688-23A

Size

1ml

Applications

FC, ICC, IHC, WB

Hosts

Mouse

Form

Supplied as a liquid, 0.7% BSA, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG2b

References

1. Kool et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5, homologs of the multidrug resistance associated protein gene (MRP1), in human cancer cell lines Cancer res. 57: 3537-3547, 1997 2. Kool et al. MRP3, an organic anion transporter able to transport anti cancer drugs. Proc. Natl. Acad. Sci. USA 96: 6915-9, 1999.

Additional Info

Recognizes an internal epitope of MRP3, a 190-200kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. Does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products.