MRPS11, ID (MRPS11, RPMS11, 28S ribosomal protein S11, mitochondrial, Cervical cancer proto-oncogene 2 protein) (FITC)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

038605-FITC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Ishiguchi, H., et al. Int. J. Cancer 111(6):900-909(2004)\nZhang, Z., et al. Genomics 81(5):468-480(2003)\nKenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :\nSuzuki, T., et al. J. Biol. Chem. 276(35):33181-33195(2001)\nCavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)

Additional Info

Human

Alternative Names

MRPS11, RPMS11, 28S ribosomal protein S11, mitochondrial, Cervical cancer proto-oncogene 2 protein