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MST1/2 (M178) pAb

MST1/2 (M178) pAb

Cat no: BS1554

Supplier: Bioworld Technology, Inc.
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Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an Nterminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK< JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily.
Catalogue number: BS1554
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q13043
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 150-200 of Human MST1.
Species: MST1/2 (M178) pAb detects endogenous levels of MST1/2 protein.
Molecular weight: ~ 65 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: STE20-like kinase MST1; Mammalian STE20-like protein kinase 1; Serine/threonine protein kinase 4; Serine/threonine protein kinase Krs-2
Additional info: For research use only, not for use in diagnostic procedure.

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