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MXD3, Recombinant, Human, aa1-206, His-Tag (Max Dimerization Protein 3, BHLHC13, MAD3, MYX)

Cat no: 138701

MXD3, Recombinant, Human, aa1-206, His-Tag (Max Dimerization Protein 3, BHLHC13, MAD3, MYX)

MXD3 is a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described. \n\nSource:\nRecombinant protein corresponding to aa1-206 from human MXD3 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~25.9kD (229aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMEPLASN IQVLLQAAEF LERREREAEH GYASLCPHRS PGPIHRRKKR PPQAPGAQDS GRSVHNELEK RRRAQLKRCL ERLKQQMPLG ADCARYTTLS LLRRARMHIQ KLEDQEQRAR QLKERLRSKQ QSLQRQLEQL RGLAGAAERE RLRADSLDSS GLSSERSDSD QEELEVDVES LVFGGEAELL RGFVAGQEHS YSHGGGAWL\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138701

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Yun JS, Rust JM, et al. (2007). Mol Cell Biol. 27(23):8178-89. 2. Barisone GA, Yun JS, et al. (2008). Cell Cycle. 7(4):423-7.

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

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Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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