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Myotubularin (Y290) Peptide

Myotubularin (Y290) Peptide

Cat no: BS2971P

Supplier: Bioworld Technology, Inc.
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Human MTM1, a 603 amino-acid protein, is mutated in myotubular myopathy. The largely related protein hMTMR2 is found mutated in a recessive form of Charcot-Marie-tooth neuropathy. Myotubularin is primarily a lipid phosphatase that acts on hosphatidylinositol 3-monophosphate and is involved in the regulation of the phosphatidylinositol 3-kinase (PI 3-kinase) pathway and membrane trafficking. Wildtype myotubularin can directly dephosphorylate PI 3-P and PI 4-P in vitro. Thus, it decreases PI 3-P levels by down-regulating PI 3-K activity and by facilitating the degradation of PI 3-P.
Catalogue number: BS2971P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13496
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Myotubularin (Y290). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: AF073996; CG2; CNM; CNM; KIAA4176; mKIAA4176; Mtm; Mtm1; MTM1; MTMX; MTMX; Myotubular myopathy 1; Myotubular myopathy 1; Myotubularin; XLMTM; XLMTM;
Additional info: This peptide can be used with studies using BS2971 Myotubularin (Y290) pAb.

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