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Na+ CP type (alpha)-pan (E1476) pAb

Na+ CP type (alpha)-pan (E1476) pAb

Cat no: BS3558

Supplier: Bioworld Technology, Inc.
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Voltage-gated Na+ channels regulate the permeability of excitable cells to sodium ions. During the propagation of an action potential, Na+ channels allow an influx of sodium ions, which rapidly depolarize the cell. The sodium channel protein is comprised of one (alpha) subunit and two (beta) subunits. The Na+ CP type I and Na+ CP type II(alpha) subunits are expressed in adult brain. Na+ CP type III(alpha) is expressed in embryonic brain, but not in adult brain. Na+ CP type III(beta) is a 215 amino acid, single-pass type I membrane protein that modulates sodium channel gating kinetics and inactivates the channel opening more slowly than the I(beta) subunit. It has an extracellular N-terminal domain, an N-terminal signal sequence, a single membrane-spanning region and a C-terminal cytoplasmic region.
Catalogue number: BS3558
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 100ug/100ul
Swiss prot: Q15858
Dilutions: IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 1442-1496 of Human Na+ CP type (alpha)-pan.
Species: Na+ CP type (alpha)-pan (E1476) pAb detects endogenous levels of Na+ CP type (alpha)-pan protein.
Molecular weight: ~ 226 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: ETHA; hNE Na; hNE-Na; hNENa; NE NA; NENA; Neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN9A; SCN9A; Sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; Sodium channel voltage gated type IX alpha; Sodium channel voltage gated type IX alpha polypeptide; Sodium channel voltage gated type IX alpha subunit; Voltage gated sodium channel alpha subunit Nav1.7; Voltage gated sodium channel subunit alpha Nav1; Voltage-gate
Additional info: For research use only, not for use in diagnostic procedure.

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