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Na+ CP type II(alpha) (K1032) pAb

Na+ CP type II(alpha) (K1032) pAb

Cat no: BS3562

Supplier: Bioworld Technology, Inc.
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Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The (alpha) subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type II(alpha) subunits are more abundant along axons. The (beta)1 subunit of sodium channel type I is expressed in brain, skeletal and cardiac muscle. In the brain, (beta)1 and (beta)2 are highly expressed in Purkinje cells, and (beta)1 is also expressed in the pyramidal cells of the deep cerebellar nuclei. Impaired voltage-gated sodium channels lead to a number of diseases including myotonia.
Catalogue number: BS3562
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 100ug/100ul
Swiss prot: Q99250
Dilutions: IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 1002-1052 of Human Na+ CP type II(alpha).
Species: Na+ CP type II(alpha) (K1032) pAb detects endogenous levels of Na+ CP type II(alpha) protein.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: SCN2A; NAC2; SCN2A1; SCN2A2; HBSC II; Sodium channel protein type 2 subunit alpha
Additional info: For research use only, not for use in diagnostic procedure.

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