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Na+ CP type IIbeta Peptide

Cat no: BS5811P

Na+ CP type IIbeta Peptide

Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IIbeta (sodium channel, voltage-gated, typeII, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type IIbeta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.

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SPECIFICATIONS

Catalog Number

BS5811P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Na+ CP type IIbeta. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O60939

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5811 Na+ CP type IIbeta pAb.

Alternative Names

Sodium channel subunit beta-2; SCN2B; ORF Names: UNQ326/PRO386; Na+ CP typeIIbeta

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