NDRG4 (G217) pAb

The N-Myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65% homology. NDRG4 (NDRG family member 4), also known as SMAP8 (smooth muscle-associated protein 8) or BDM1 (brain development-related molecule 1), is a 352 amino acid cytoplasmic protein that belongs to the NDRG family. Expressed specifically in brain and heart, NDRG4 is thought to function as a regulator of mitogenic signaling in vascular smooth muscle cells. Additionally, NDRG4 may play a role in early postnatal development and may mediate the differentiation and subsequent function of neuronal cells. NDRG4 is expressed as six isoforms (the first three of which are designated NDRG4- BVar, NDRG4-B and NDRG4-H) due to alternative splicing events.

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SPECIFICATIONS

Catalog Number

BS3378

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 187-230 of Human NDRG4.

Species

NDRG4 (G217) pAb detects endogenous levels of NDRG4 protein.

Dilutions

WB: 1:500~1:1000\nIHC: 1:50~1:200

Swiss Prot

Q9ULP0

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 34 kDa

Alternative Names

Protein NDRG4; Brain development-related molecule 1; N-myc downstream-regulated gene 4 protein; Vascular smooth muscle cell-associated protein 8; SMAP-8; BDM1; KIAA1180; NDRG4