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Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5,6-tetramethylenothienopyrimidin-4-one-2-mercaptoethylcyanide)

Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5,6-tetramethylenothienopyrimidin-4-one-2-mercaptoethylcyanide)

Cat no: 045074

Supplier: United States Biological
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Necroptosis inhibitor. Indirect RIP1 kinase inhibitor. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: +4 degrees C Stable for at least 2 years after receipt when stored at +4 degrees C.
Catalogue number: 045074
Size: 5mg
Purity: >98% (NMR)
Alternative names: Nec-5, 3-p-Methoxyphenyl-5,6-tetramethylenothienopyrimidin-4-one-2-mercaptoethylcyanide
References: Product Reference: ?Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5: K. Wang, et al.; Bioorg. Med. Chem. Lett. 17, 1455 (2007) ?Idenfication of RIP1 kinase as a specific cellular target of necrostatins: A. Degterev, et al.; Nat. Chem. Biol. 4, 313 (2008) ?

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