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Neoantimycin

Neoantimycin

Cat no: N1011

Supplier: United States Biological
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Neoantimycin is a rare and unusual ring-extended member of the antimycin class. Neoantimycin is produced by a Streptomyces species unrelated to antimycin-producing strains. Literature references to neoantimycin are limited but the recent discovery of the closely related metabolite, prunustatin A, as a selective GRP78 molecular chaperone down-regulator highlights the potential of this class as research probes. In-house screening at Microbial Screening Technologies has shown the metabolite to possess potent nematocidal and antitumor activity with only limited antifungal activity. Purity: > 95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Catalogue number: N1011
Size: 500ug
Purity: > 95% by HPLC
References: 1. The structure of neoantimycin. Caglioti L. Tetrahedron 1969, 25, 2193. 2. Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger. Umeda Y. et al. J Antibiot. 2005, 58, 206.

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