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Nephrin (H892) Peptide

Nephrin (H892) Peptide

Cat no: BS3462P

Supplier: Bioworld Technology, Inc.
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Nephrin is a member of the immunoglobulin family of cell adhesion molecules that localizes to opposing sites of the secondary foot processes formed by podocytes, a specialized epithelial cell that ensures size- and charge-selective ultrafiltration. The human nephrin gene maps to chromosome 19q13.1 and encodes a 1,241 amino acid protein that contains a transmembrane domain, 8 Ig-like modules, and 1 fibronectin III-like module. Nephrin is expressed in embryonic and adult kidneys and localizes to glomerular podocytes and the glomerular slit diaphragm. Nephrin stimulates mitogen-activated protein kinases and is enhanced by podocin, which binds to the cytoplasmic tail of nephrin.
Catalogue number: BS3462P
Applications: Block/Neutralize/Inhibit
Swiss prot: O60500
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Nephrin (H892). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: NPHS1; CNF; NEPHRIN; NPHN
Additional info: This peptide can be used with studies using BS3462 Nephrin (H892) pAb.

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