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Nephrocystin-5 (R467) pAb

Nephrocystin-5 (R467) pAb

Cat no: BS3319


Supplier: Bioworld Technology, Inc.
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CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. CEP290 is ubiquitously expressed; strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5), Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.
Catalogue number: BS3319
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q15051
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 432-486 of Human Nephrocystin-5.
Species: Nephrocystin-5 (R467) pAb detects endogenous levels of Nephrocystin-5 protein.
Molecular weight: ~ 69 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 3H11AG; BBS14; CT87; JBTS5; JBTS6; LCA10; MKS4; NPHP6; Nephrocystin 6; SLSN6 1; 2; 5; rd16; CTCL tumor antigen se2 2; Cancer/testis antigen 87; Centrosomal protein 290kDa; Monoclonal antibody 3H11 antigen; Prostate cancer antigen T21
Additional info: For research use only, not for use in diagnostic procedure.

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