Neurocan Peptide

Cat no: BS5819P

Supplier: Bioworld Technology, Inc.

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The lecticans are a family of chondroitin proteoglycans, including aggrecan, versican, neurocan and brevican, that contain a C-type lectin domain. Neurocan is a glycoprotein synthesized primarily by neurons, and its expression levels are highest during embryonic brain development and during the early postnatal period. Neurocan is a component of the extracellular matrix in the central nervous system that can bind to various other CNS matrix components, such as heparin, Tenascin-R, HB-GAM and NCAM, suggesting that it plays a role in axon guidance and neurite growth. Neurocan is a 1,257 amino acid, precursor protein in embryonic and neonatal rats that is proteolytically proc-essed in the adult CNS into an N-terminal fragment, which localizes to the cytoplasm of glial cells. Neurocan expression (including the re-expression of the neonatal isoform) increases significantly in adults in the glial scar resulting from cortical injury.

Catalogue number:	BS5819P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O14594
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Neurocan. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3; NEUR
Additional info:	This peptide can be used with studies using BS5819 Neurocan pAb.

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Neurocan Peptide

Cat no: BS5819P

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