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NIPA (S350) Peptide

NIPA (S350) Peptide

Cat no: BS1847P


Supplier: Bioworld Technology, Inc.
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Entry into mitosis is essentially driven by cyclin B1 which is located in the cytoplasm throughout interphase, but accumulates in the nucleus just before mitosis occurs. Nuclear Interaction Partner of ALK (NIPA) plays a critical role in cyclin B1 regulation. NIPA is normally phosphorylated during G2 and M phases, resulting in an accumulation of cyclin B1. When NIPA sheds its attached phosphate, it binds to SCF to form the SCFNIPA complex, a member of the E3 ubiquitin ligases, which ubiquitinates cyclin B1, thereby targeting it to the proteosome for degradation.
Catalogue number: BS1847P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q86WB0
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide NIPA (S350). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Nuclear-interacting partner of ALK; Nuclear-interacting partner of anaplastic lymphoma kinase; hNIPA; Zinc finger C3HC-type protein 1; HSPC216; NIPA; ZC3HC1
Additional info: This peptide can be used with studies using BS1847 NIPA (S350) pAb.

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