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NK-3R (P434) pAb

NK-3R (P434) pAb

Cat no: BS2736

Supplier: Bioworld Technology, Inc.
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Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II.
Catalogue number: BS2736
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: P29371
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 404-450 of Human NK-3R.
Species: NK-3R (P434) pAb detects endogenous levels of NK-3R protein.
Molecular weight: ~ 52 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: TACR3; MGC148060; MGC148061; NK-3R; NK3R; NKR; TAC3R; TAC3RL
Additional info: For research use only, not for use in diagnostic procedure.

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