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NM23-H2 (H118) pAb

NM23-H2 (H118) pAb

Cat no: BS1415

Supplier: Bioworld Technology, Inc.
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The nm23 protein is the collective designation for two closely related proteins encoded by the genes nm23H1 and nm23H2 now called NME1 and NME2. The protein is expressed in the nucleus and cytoplasm of all normal cells, and on the cell surface of many haematopoietic cells, including erythrocytes. Tumour cells with a high metastatic potential often lack or express only a low amount of nm23 protein, hence the nm23 protein has been described as a metastasis suppressor protein. Recent studies, however, suggest a more complex relationship between occurrence of the nm23 protein and metastatic activity.
Catalogue number: BS1415
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P22392
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 87-130 of Human NM23-H2.
Species: NM23/NDP Kinase B (H118) pAb detects endogenous levels of NM23/NDP Kinase B protein.
Molecular weight: ~ 23 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Nucleoside diphosphate kinase B; NDK B; NDP kinase B; nm23-H2; C-myc purine-binding transcription factor PUF
Additional info: For research use only, not for use in diagnostic procedure.

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