NMDA 2b Receptor (NMDA R2b, N-methyl-D-aspartate, GRIN2B, Glutamate receptor ionotropic N-methyl D-aspartate 2B, HGNC:4586, NR2B, hNR3, N-methyl-D-aspartate receptor subunit 2B)

Supplier:

United States Biological

Cat no: N2905-30B

NMDA 2b Receptor (NMDA R2b, N-methyl-D-aspartate, GRIN2B, Glutamate receptor ionotropic N-methyl D-aspartate 2B, HGNC:4586, NR2B, hNR3, N-methyl-D-aspartate receptor subunit 2B)

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA)\n\nPositive Control: Rat Brain lysate

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SPECIFICATIONS

Catalog Number

N2905-30B

Size

100ug

Hosts

Goat

Reactivities

Hum, Rat

Form

Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Arning L, Kraus PH, Valentin S, Saft C, Andrich J, Epplen JT. NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. Neurogenetics. 2005 Feb;6(1):25-8. Epub 2004 Nov 17. PMID: 15742215

Additional Info

Species Crossreactivity: Rat. Other species not tested. Expected based upon sequence homology: Mouse, Rat, canine

Alternative Names

Glutamate receptor ionotropic N-methyl D-aspartate 2B, HGNC:4586, NMDA R2B, NR2B, hNR3, N-methyl-D-aspartate receptor subunit 2B

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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FC, IHC, IP

Hosts

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Reactivities

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United States Biological

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Reactivities

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United States Biological

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Applications

FC, IHC

Hosts

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