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NMDAE2 (S1468) Peptide

Cat no: BS2434P

NMDAE2 (S1468) Peptide

NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA).Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease and also epilepsy and ischemic neuronal cell death.

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SPECIFICATIONS

Catalog Number

BS2434P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide NMDAE2 (S1468). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q13224

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2434 NMDAE2 (S1468) pAb.

Alternative Names

PHOSPHORYLATED AT TYR1252; N-methyl D-aspartate receptor subtype 2B; NR2B; NMDAR2B; Grin2b

SUPPLIER INFO

Bioworld Technology, Inc.

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