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NMDAE3 (P986) Peptide

NMDAE3 (P986) Peptide

Cat no: BS3541P


Supplier: Bioworld Technology, Inc.
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Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: E 1, 2, 3, 4 and one ? subunit. The ? subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
Catalogue number: BS3541P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q14957
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide NMDAE3 (P986). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Glutamate receptor ionotropic; NMDA 2C; GluN2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NR2C; NMDAR2C; GRIN2C
Additional info: This peptide can be used with studies using BS3541 NMDAE3 (P986) pAb.

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