NMDAE3 (P986) Peptide

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: E 1, 2, 3, 4 and one ? subunit. The ? subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

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SPECIFICATIONS

Catalog Number

BS3541P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide NMDAE3 (P986). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q14957

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3541 NMDAE3 (P986) pAb.

Alternative Names

Glutamate receptor ionotropic; NMDA 2C; GluN2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NR2C; NMDAR2C; GRIN2C