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Noggin, Recombinant, Human

Cat no: N3100

Noggin, Recombinant, Human

Noggin belongs to a group of structurally diverse diffusible proteins which bind TGF-beta ligands and inhibit their access to membrane receptors. This natural antagonist displays high binding-affinity for BMP-2 and -4 and a lower affinity for BMP-7 (OP-1). This protein is secreted as a disulfide-linked homodimer, however the non-disulfide-linked also assume dimeric structure and displays similar biological activity. Recombinant human Noggin is a 23.1kD non-disulfide-linked homodimer consisting of 206 amino acid residues.\n\nBiological

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SPECIFICATIONS

Catalog Number

N3100

Size

5ug

Form

Supplied as a lyophilized powder with no additives. Reconstitute with 10mM Acetic acid to 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers and stored in working aliquots at -20 degrees C. NOTE: Due to solubility reasons the protein should be kept at low pH.

Purity

(same/more than) 95% by SDS-PAGE gel and HPLC analyse. Endotoxin: (same/less than) 0.1ng/ug (1EU/ug)

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