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Nogo A (E499) pAb

Nogo A (E499) pAb

Cat no: BS2888


Supplier: Bioworld Technology, Inc.
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CNS white matter is selectively inhibitory for axonal out-growth. Nogo (also designated NI250 and Reticulon 4-A) is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Other members of the Reticulon protein family do not inhibit axon xtension and are thought to have a role in ER function. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo A, Nogo B and Nogo C.Nogo A and Nogo C have a molecular mass of 200-250 kDa and 22 kDa, respectively.
Catalogue number: BS2888
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q9NQC3
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 467-517 of Human Nogo A.
Species: Nogo A (E499) pAb detects endogenous levels of Nogo A protein.
Molecular weight: ~ 130 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: My043; SP1507; KIAA0886; NOGO; RTN4
Additional info: For research use only, not for use in diagnostic procedure.

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