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Nogo A (E499) Peptide

Nogo A (E499) Peptide

Cat no: BS2888P

Supplier: Bioworld Technology, Inc.
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CNS white matter is selectively inhibitory for axonal out-growth. Nogo (also designated NI250 and Reticulon 4-A) is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Other members of the Reticulon protein family do not inhibit axon xtension and are thought to have a role in ER function. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo A, Nogo B and Nogo C.Nogo A and Nogo C have a molecular mass of 200-250 kDa and 22 kDa, respectively.
Catalogue number: BS2888P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9NQC3
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Nogo A (E499). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: My043; SP1507; KIAA0886; NOGO; RTN4
Additional info: This peptide can be used with studies using BS2888 Nogo A (E499) pAb.

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