Home  >  Products  >  Nogo-R pAb
Nogo-R pAb

Nogo-R pAb

Cat no: BS60346

Supplier: Bioworld Technology, Inc.
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
CNS white matter is selectively inhibitory for axonal outgrowth. Nogo is an oligodendrocyte-specific member of the reticulon family and is a component of CNS white matter that prevents axonal regeneration in the adult CNS. Nogo is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The extracellular domain of Nogo, designated Nogo-66 inhibits axonal extension, but does not alter non-neuronal cell morphology. Expression of a brain-specific, leucine-rich-repeat protein with high affinity for Nogo-66, the Nogo-66 receptor (Nogo-R), is sufficient to impart Nogo-66 axonal inhibition to unresponsive neurons. Disruption of the interaction between Nogo-66 and Nogo-R potentially provides for enhanced recovery after human CNS injury. Nogo-R is widely expressed in the brain, with the highest levels of expression in the gray matter of the CNS. In addition, low levels of Nogo-R mRNA are expressed in heart and kidney.
Catalogue number: BS60346
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9BZR6
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: A synthetic peptide corresponding to residues in Human Nogo-R.
Species: Nogo-R pAb detects endogenous levels of Nogo-R protein.
Molecular weight: ~ 52 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Reticulon-4 receptor; Nogo receptor; NgR; Nogo-66 receptor; RTN4R; NOGOR; UNQ330/PRO526
Additional info: For research use only, not for use in diagnostic procedure.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Bioworld Technology, Inc.
Get a Quote Direct from
Bioworld Technology, Inc.

By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave