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NPM1 mAb

NPM1 mAb

Cat no: MB0086


Supplier: Bioworld Technology, Inc.
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Nucleophosmin (NPM; also known as B23, numatrin or NO38) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase (alpha) activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.
Catalogue number: MB0086
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P06748
Dilutions: WB: 1:1000 ICC: 1:100~200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human NPM1.
Species: This antibody detects endogenous levels of NPM1 and does not cross-react with related proteins
Molecular weight: Predicted band size:33KDa Observed band size:38KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Nucleophosmin; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin; NPM1; NPM
Additional info: For research use only, not for use in diagnostic procedure.

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