NTR2 (D184) Peptide

Cat no: BS2821P

Supplier: Bioworld Technology, Inc.

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Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is coexpressed with the full length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNFalpha in an ERK1/2 and Akt kinase-dependent manner.

Catalogue number:	BS2821P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O95665
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide NTR2 (D184). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Neurotensin receptor type 2; NTSR2; NT-R-2; NTR2; NTSR2
Additional info:	This peptide can be used with studies using BS2821 NTR2 (D184) pAb.

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NTR2 (D184) Peptide

Cat no: BS2821P

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