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NUP88 Peptide

NUP88 Peptide

Cat no: BS5831P

Supplier: Bioworld Technology, Inc.
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The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup88 (nucleoporin 88kDa) is a 741 amino acid protein that localizes to the nucleus and functions as an essential component of the nuclear pore complex. Expressed ubiquitously, Nup88 is subject to phosphorylation by ATM or ATR and is upregulated in malignant neoplasms and precancerous dysplasias, suggesting a role in tumorigenesis. The gene encoding Nup88 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
Catalogue number: BS5831P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q99567
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide NUP88. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88
Additional info: This peptide can be used with studies using BS5831 NUP88 pAb.

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