NVL pAb

Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase), is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is involved in a variety of membrane functions and in the regulation of the cell cycle. VCP associates with ubiquitinated IkB-a as well as with the 26S proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IkB-a. NVL (nuclear valosin-containing protein-like), also known as NVLp, is an 856 amino acid nuclear protein belonging to the AAA ATPase family. Implicated in ATP-dependent nuclear processes and ribosome synthesis, NVL exists as three alternatively spliced isoforms designated NVL isoform 1 (NVLp.2), NVL isoform 2 (NVLp.1) and NVL isoform 3. Widely expressed, NVL is found at highest levels in pancreas, retina, heart, skeletal muscle and placenta.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS5832

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 393-438 of Human NVL.

Species

NVL pAb detects endogenous levels of NVL protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

O15381

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul