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OATP1 (N286) Peptide

OATP1 (N286) Peptide

Cat no: BS3952P

Supplier: Bioworld Technology, Inc.
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The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane.
Catalogue number: BS3952P
Applications: Block/Neutralize/Inhibit
Swiss prot: P46721
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide OATP1 (N286). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: OATP; OATP-1; OATP-A; OATP1A2; Organic anion-transporting polypeptide 1; SLC21A3; SLCO1A2; SO1A2;
Additional info: This peptide can be used with studies using BS3952 OATP1 (N286) pAb.

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