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OB-cadherin (K444) Peptide

Cat no: BS2684P

OB-cadherin (K444) Peptide

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. Two forms of OB-cadherin (for osteoblast-cadherin, also designated cadherin-11 or OSF-4) have been identified as OBcadherin- 1 and OB-cadherin-2. Both OB-cadherins are expressed in osteoblastic cell lines and low expression is also seen in lungs, testis and brain. OB-cadherin-2 has a truncated cytoplasmic domain.

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SPECIFICATIONS

Catalog Number

BS2684P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide OB-cadherin (K444). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P55287

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2684 OB-cadherin (K444) pAb.

Alternative Names

CDH11; CAD11; CDHOB; OB; OB-CADHERIN; OSF-4; OSTEOBLAST-CADHERIN

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