OCRL (Q199) Peptide

Cat no: BS2951P

Supplier: Bioworld Technology, Inc.

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The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. OCRL1 is a type II 5-phosphatase that is mutated in the oculocerebrorenal syndrome of Lowe (OCRL). OCRL is a rare X-linked disorder that is characterized in part by congenital cataracts, mental retardation, muscular hypotonia and renal tubular dysfunction.OCRL1 has a high affinity for phosphatidylinositol 4,5-bisphosphate as well as inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate as substrates. OCRL1 is localized to the Golgi complex and is thought to be part of the trans-Golgi network (TGN), which suggests that OCRL1 plays a role in protein sorting and trafficking within the cell.

Catalogue number:	BS2951P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q01968
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide OCRL (Q199). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Inositol polyphosphate 5-phosphatase OCRL-1; Lowe oculocerebrorenal syndrome protein; INPP5F; OCRL1; OCRL
Additional info:	This peptide can be used with studies using BS2951 OCRL (Q199) pAb.

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OCRL (Q199) Peptide

Cat no: BS2951P

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