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Okadaic Acid, Sodium salt (Halochondrine A)

Cat no: O5800


Supplier: United States Biological
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Okadaic Acid, a marine toxin, polyether derivative produced by dinoflagellates, is a potent, cell-permeable, specific inhibitor of PP-1 and PP-2 serine/threonine-speci?c protein phosphatases in a variety of cell types. Salt form of okadaic acid, with somewhat greater stability than the free acid when stored in organic solvents. Source: Prorocentrum concavum Solubility: Soluble in DMSO or ethanol. Storage and Stability: Light Sensitive. Store at -20 degrees C. Stable as a powder for at least 12 months. Stable as a liquid for 6 months. WARNING: Highly irritant to skin and mucous membranes. SPECIAL HAZARD: TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure.
Catalogue number: O5800
Size: 100ug
Form: Supplied as white powder.
Purity: Purified by preparative flash, medium pressure nad high performance liquid chromatography.
Alternative names: 9,10-Deepithio-9,10-didehydroacanthifolicin, halochondrine A
References: Haystead et al., Nature 337:78, 1989 Redpath and Proud, Biochem. J. 262:69, 1989 Takai, J. Mus. Res. & Cell Motil. 9:563, 1988 Wheat et al., Mol. Cell. Biol. 14:5881, 1994 Amara, F. M. et al.: Defining a Novel cis-Element in the 3

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