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ORC1 Peptide

ORC1 Peptide

Cat no: BS5836P

Supplier: Bioworld Technology, Inc.
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ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells.
Catalogue number: BS5836P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13415
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ORC1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Origin recognition complex subunit 1; Replication control protein 1; ORC1L; PARC1
Additional info: This peptide can be used with studies using BS5836 ORC1 pAb.

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