ORCTL2 (L395) pAb

ORCTL2 (organic cation transporter-like protein 2), also known as HET, ITM, BWR1A, IMPT1, TSSC5, BWSCR1A, SLC22A1L, p45-BWR1A or SLC22A18, is a 424 amino acid multi-pass membrane protein that localizes at the apical membrane surface of renal proximal tubules. ORCTL2 is expressed at high levels in the kidney, liver, colon and in fetal renal proximal tubules and present at lower levels in heart, brain and lung. Belonging to the major facilitator superfamily, ORCTL2 may act as a transporter of organic cations based on a proton efflux antiport mechanism and may also play a role in the transport of chloroquine and quinidine-related compounds in kidney. Defects in ORCTL2 are associated with breast and lung cancer and are the cause of rhabdomyosarcoma type 1, a malignant tumor derived from striated muscle.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS2122

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 360-412 of Human ORCTL2.

Species

ORCTL2 (L395) pAb detects endogenous levels of ORCTL2 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

Q96BI1

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 43 kDa

Alternative Names

Beckwith Wiedemann syndrome chromosomal region 1 candidate gene A protein; BWR1A; BWSCR1A; DKFZp667A184; Efflux transporter like protein; HET; Imprinted multi membrane spanning polyspecific transporter related protein 1; IMPT1; ITM; MGC94186; ORCTL 2; ORCTL2; Organic cation transporter like protein 2; OTTMUSP00000030799; OTTMUSP00000030800; p45 Beckwith Wiedemann region 1 A; p45 BWR1A; SLC22A18; SLC22A1L; Solute carrier family 22 member 1 like; TSSC5; TSSC5v; Tumor suppress