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OXSR1 Peptide

OXSR1 Peptide

Cat no: BS5837P

Supplier: Bioworld Technology, Inc.
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Oxidative stress-responsive 1 protein (OXSR1), a protein of 527 amino acids, belongs to the STE20 subfamily. OXSR1 is one of two human homologs of Fray, a serine/threonine kinase expressed in Drosophila. OXSR1 binds to and phosphorylates p21-activated protein kinase PAK1 and regulates downstream kinases in response to environmental stress. Endogenous OXSR1 is activated only by osmotic stresses, notably sorbitol and to a lesser extent NaCl. OXSR1 may also play a role in regulating the actin cytoskeleton. The chloride channel proteins SLC12A1, SLC12A2, and SLC12A6 isoform 2 interact with OXSR1, but SLC12A4 and SLC12A7 do not. The WNK1 and WNK4 protein kinases activate OXSR1 by phosphorlating its T-loop. The OXSR1 protein is widely expressed in mammalian tissues.
Catalogue number: BS5837P
Applications: Block/Neutralize/Inhibit
Swiss prot: O95747
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide OXSR1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein; KIAA1101; OSR1
Additional info: This peptide can be used with studies using BS5837 OXSR1 pAb.

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