p-ABL1/2 (Y393/439) Peptide

Cat no: BS4727P

Supplier: Bioworld Technology, Inc.

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The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including 90-95% of chronic myelocytic leukemia (CML), 20-25% of adult acute lymphoblastic leukemia (ALL) and 2-5% of pediatric ALL. In these leukemias the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein-tyrosine kinase.

Catalogue number:	BS4727P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P00519/P42684
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-ABL1/2 (Y393/439). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ABL1; ABL2; ABL; JTK7; p150; Proto-oncogene c-Abl; Tyrosine-protein kinase ABL1; c-Abl; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG; ABLL; ARG
Additional info:	This peptide can be used with studies using BS4727 p-ABL1/2 (Y393/439) pAb.

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p-ABL1/2 (Y393/439) Peptide

Cat no: BS4727P

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