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p-Adducin (alpha)/(beta) (S726/713) pAb

p-Adducin (alpha)/(beta) (S726/713) pAb

Cat no: BS4005

Supplier: Bioworld Technology, Inc.
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Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Catalogue number: BS4005
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P35611/P35612
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human Adducin (alpha) around the phosphorylation site of Serine 726.
Species: p-Adducin (alpha)/(beta) (S726/713) pAb detects endogenous levels of Adducin (alpha) protein only when phosphorylated at Ser726 and Adducin (beta) protein only when phosphorylated at Ser713.
Molecular weight: ~ 81 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-adducin; Erythrocyte adducin subunit alpha; ADD1; ADDA; (alpha)-Adducin; Adducin1; Adducin-1; (alpha) Adducin; Adducin-(alpha); Beta-adducin; Erythrocyte adducin subunit beta; ADD2; ADDB; (beta)-Adducin; Adducin1; Adducin-1; (beta) Adducin; Adducin (beta); Adducin-(beta)
Additional info: For research use only, not for use in diagnostic procedure.

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